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This second edition of a very successful vascular surgery text was developed in order to address significant changes that have occurred in contemporary vascular surgery and to highlight new information that has developed regarding vascular imaging, interventional and endovascular procedures. The overall length of the text is slightly shorter than the first edition with relevant core chapters being retained to emphasize the basic science nature of the text, with approximately 60% of the material undergoing major revisions or being new chapters. The significant change from the first text is an emphasis on vascular pathology and physiology that is relevant to current practice including information that is currently included on the vascular board examinations. A new emphasis on endovascular therapies has been added by including five chapters on endovascular techniques and an additional section with six chapters comparing conventional vascular reconstruction to endovascular methods. These new chapters address the most important issue in contemporary vascular surgery, i.e., the role of endovascular methods in treating vascular lesions and the impact that this has on training and credentialing. A unique aspect of this book differentiating it from other texts is a comparison of conventional methods with the endovascular techniques. Overall the text provides a comprehensive perspective of contemporary vascular surgery and future perspectives. The authors are preeminent in the field and are most capable for addressing the assigned topics with the goals being to provide an updated and forward looking text that accommodates the needs of practicing and training vascular surgeons. CONTENTS Part I. Vascular Pathology and Physiology. 1. Embryology and Development of the Vascular System. (C. Phifer Nicholson, Peter Gloviczki). 2. Vascular Wall Physiology. (Christian C. Haudenschild). 3. Homeostasis and Coagulation. (Jonathan B. Towne). 4. Molecular Aspects of Atherosclerosis. (J. Jeffrey Alexander, John A. Moawad, MD). 5. Localization of Atherosclerosis Lesions. (Christopher K. Zarins). 6. Pathogenesis of Arterial Fibrodysplasia. (James C. Stanley). 7. Physiology of Vasospastic Disorders. (Scott E. Musicant, Christian T. Harker, Jean-Baptiste Roullet, James M. Edwards, Gregory L. Moneta). 8. Buerger's Disease. (John Blebea, Richard F. Kempczinski). 9. Ergotism. (Roger F. J. Shepherd). 10. Arteritis. (Francis J. Kazmier). 11. Adventitial Cystic Disease. (Carlos E. Donayre). 12. Entrapment Syndromes. (Carlos E. Donayre). 13. Intimal Hyperplasia. (Ted R. Kohler). 14. Thoracic Outlet Syndrome. (Herbert I. Machleder). 15. Aneurysmal Disease. (Samuel Eric Wilson, Juan Carlos Jimenez). 16. Pathophysiology of Renovascular Hypertension. (Kimberley J. Hansen, Richard H. Dean, David L. Robaczewski). 17. Pathophysiology, Hemodynamics, and Complications of Venous Disease. (Thomas F. O'Donnell, Jr., Mark Iafrati). 18. Physiologic Changes in Lymphatic Dysfunction. (Peter Gloviczki). 19. Physiologic Changes in Visceral Ischemia. (Bruce L. Gewertz). 20. Natural History of Atherosclerosis in the Lower Extremity, Carotid, and Coronary Circulations. (Daniel B. Walsh). 21. Neurologic Basis for Sympathetically Maintained Pain: Causalgia and Reflex Sympathetic Dystrophy. (Marco Scoccianti, Rodney A. White). 22. Compartment Syndromes Physiology. (Malcolm O. Perry). 23. Physiology of Reperfusion Injury. (D. Neil Granger, Shervanthi Homer-Vannlasinkam). 24. Cerebral Ischemia. (Christian deVirgilio). 25. Pathophysiology of Spinal Cord Ischemia. (Larry H. Hollier). 26. Vascular Erectile Dysfunction: Mechanisms and Current Approaches. (Ralph G. DePalma). 27. Portal Hypertension: Pathophysiology and Clinical Correlates. (David Rigberg and Hugh A. Gelabert). Part II. Noninvasive Vascular Diagnostics. 28. Physiologic Basis of Hemodynamic Measurement. (R. Eugene Zierler). 29. Spectral Analysis. (Christopher R.B. Merritt). 30. Ultrasound Imaging. (Christopher R.B. Merritt). 31. Radionuclide Scanning. (Robert E. Sonnemaker). 32. Computed Tomography. (Anthony W. Stanson). 33. Magnetic Resonance Imaging. (David Saloner, Charles M. Anderson, Gary R. Caputo). Part III. Invasive Vascular Diagnostics. 34. Angiography. (C. Mark Mehringer). 35. Intravascular Ultrasound. (James T. Lee). 36. Angioscopy in Peripheral Vascular Surgery. (Arnold Miller). Part IV. Medical Management. 37. Atherosclerosis: Risk Factor and Medical Management. (Ralph G. DePalma). 38. Pharmacologic Intervention: Thrombolytic Therapy. (Anthony J. Comerota). 39. Pharmacologic Intervention: Vasodilation Therapy and Rheologic Agents. (George Johnson, Jr.). 40. Pharmacologic Intervention: Lipid-Lowering Agents. (Ralph G. dePalma). 41. Infections and Antibiotics in Vascular Surgery. (Martin R. Back). Part V. Endovascular Interventions for Vascular Disease. 42. Catheter-Based Approaches to the Treatment of Atheroembolic Disease. (Thomas J. Fogarty). 43. Balloon Angioplasty and Transluminal Recanalization. (Stephen R. Ramee). 44. Intravascular Stents. (Frank J. Criado). 45. Endovascular Prostheses for repair of Abdominal Aortic Aneurysms. (Carlos E. Donayre). Part VI. Comparison of Conventional Vascular Reconstruction and Endovascular Techniques. 46. Surgical and Endovascular treatment of Chronic Ischemia of the Lower Limbs. (Frans Moll, Jean Paul MP de Vrias, Jos.C. van den Berg). 47. Aortoiliac Endovascular Recanalization Compared to Surgical Reconstruction. (Michael L. Marin, Peter L. Farias). 48. Endovascular stent-graft repair of Thoracic Aortic Aneurysms and Dissections. (Larry H. Hollier). 49. Brachiocephalic Vascular Reconstructions Compared with Endovascular Repair. (Edward B. Diethrich). 50. Carotid Endarterectomy Compared with Carotid Angioplasty and Stenting. (L. Nelson Hopkins). 51. Endovascular Intervention for Venous Occlusion Compared with Surgical Reconstruction. (Patricia E.Thorpe and Francisco J. Osse).
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