Covering the spectrum of cognitive decline in aging using illustrative cases, from mild impairment to dementia, this set of case studies offers a wide-ranging guide for trainees and clinicians. This second volume includes updated research diagnostic criteria and details of new imaging technology, including novel biomarkers such as PET amyloid and tau, to inform readers in clinical practice. Each case includes a clinical history, examination findings and special investigations, followed by diagnosis and discussion, to encourage clinical reasoning, integrative thinking, and problem-solving skills. To reinforce diagnostic skills, the cases include careful analysis of individual presenting patterns and up-to-date information on diagnostic classification and tools. The reader will be able to distinguish patients who need reassurance, closer follow-up or immediate referral to specialized services. With an international authorship, this book is for trainees and clinicians in neurology, psychiatry and neuropsychology.
This second volume contains updated diagnostic criteria and new biomarker technologies, such as PET amyloid and tau, to enable effective clinical practice
An international authorship ensures that this collection of case studies is comprehensive and globally relevant
Easy-to-read and clearly written, these case studies will inform and assist clinical practice, and ensure clinical knowledge is up to date
Table of Contents
1. A young missionary with problems for quoting the Bible
2. Care planning and decision making through the stages of dementia
3. What is typical and atypical in dementia?
4. Elderly man repeating questions about upcoming appointments
5. A devoted wife with an atypical finding
6. A challenging thesis
7. A 59 year-old dysexecutive clerk
8. FTD – behavioral variant frontotemporal dementia
9. A 59 year-old man with weakness and personality changes
10. A woman with progressive episodic memory loss and personality change
11. A man with progressive memory loss and a strong family history of progressive dementia
12. Long day's journey into night: when the pre-symptomatic phase evolves into manifest disease
13. Right temporal variant frontotemporal dementia
14. I'm having trouble working with my spreadsheets
15. Speechless at first sight
16. De novo artistic talent in a patient with progressive speech problems
17. From stuttering to mutism: speech and language deterioration in neurodegenerative disease
18. Primary progressive aphasia: logopenic progressive aphasia
19. Alexia without agraphia in a patient with pathologically identified Pick's disease
20. A meaningless world
21. Obsessive mandala drawing in semantic dementia
22. Forced into retirement
23. Who are these people in my living room?
24. This case of Parkinsonism that never had a good response to Levodopa
25. Common complaints: rare pathology
26. Tremor, hallucinations and cognitive decline
27. Acute behavioral changes with cognitive impairment
28. Vascular cognitive impairment
29. Rapidly progressive behavioral changes and cognitive symptoms in a 29-year-old woman
30. Hashimoto's encephalopathy as treatable dementia
31. Hydrocephalus and CSF-related dementia
32. Something very wrong happened very fast
33. Siblings with a fatal cause of rapidly progressive dementia
34. Young women with bipolar disorder history.
Pedro Rosa-Neto, McGill University, Montréal
Serge Gauthier is the Director of the AD and Related Disorders Unit at McGill University, Montréal Research Centre for Studies in Aging and Professor in the Departments of Neurology and Neurosurgery, Psychiatry and Medicine at McGill University, Montréal.
Serge Gauthier, McGill University, Montréal
Pedro Rosa-Neto is an Associate Professor of Neurology, Neurosurgery and Psychiatry and Director of the McGill University, Montréal Research Centre for Studies in Aging. He is also a researcher at the Douglas Institute, Montreal, Canada.
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