Contents:
Dedication
Foreword
List of Contributors
Chapter 1. Introduction and Historical Perspectives on Image-Guided Surgery
Stereotactic Frames
Advent of Volumetric Tomography
Image Guidance
Optical Localization
Registration
Beyond Points
Intraoperative Imaging
Deformation Correction
Work Underway
Dedication
References
Section I: Methods
Chapter 2. Background on Imaging Structural Imaging
Introduction
Basic Magnetic Resonance Imaging
CT/Dynamic CTA/CT Perfusion
Safety of CT and MRI
Conclusion
References
Chapter 3. Advanced Functional Imaging: fMRI, PET, and MEG
Introduction
Positron Emission Tomography
Functional Magnetic Resonance Imaging
Magnetoencephalography
Conclusion
References
Chapter 4. Imaging White Matter Anatomy for Brain Tumor Surgery
Introduction
Theoretical Foundations of Diffusion MRI
Diffusion MRI in Practice: Image Acquisition Artifacts
Diffusion Tensor Imaging
High Angular Resolution Diffusion Imaging
Diffusion MRI Tractography
Conclusion
References
Chapter 5. Background on Stereotaxis
Introduction
Laboratory Work
First Human Stereotaxis
Development of Computational Stereotaxy and Image Guidance
References
Chapter 6. Role of Computers and Image Processing in Image-Guided Brain Tumor Surgery
Introduction
Segmentation
Tractography
Registration
Navigation
Conclusion
References
Chapter 7. Intraoperative Imaging
Introduction: Intraoperative Imaging Modalities
Navigation and Imaging
Intraoperative X-ray Fluoroscopy and Intraoperative Angiography
Intraoperative Fluorescence Techniques and Others
Intraoperative Ultrasound
Intraoperative CT
Introduction to Intraoperative MRI
Outlook
References
Section II: Applications
Chapter 8. Image-Guided Brain Biopsy
Brain Biopsy v. Advanced Imaging: Why Do We Still Need Brain Biopsies in the Age of PET, MRS and Molecular Imaging?
Multimodal Imaging for Brain Biopsy: CT, MR, PET, MRS, SPECT
Open, Frameless, or Frame-based Stereotactic Biopsies
Biopsy Instruments: Seldinger Needle, Backlund Spiral, Microforceps
Neoplastic v. Non-Neoplastic Lesions
Nonfocal Disease: Leukencephalopathies and Neurodegenerative Diseases
Results: Diagnostic Yield
Complications
Biopsies in Eloquent, Functional Areas: Brainstem, Pineal Region, Suprasellar Region
Future Directions: Molecular Neuropathology
Conclusion
References
Chapter 9. Multimodal Image-Guided Brain Tumor Resection
Introduction
Types of Image Guidance in Brain Tumor Resection
Clinical Applications
Future Directions
Conclusions
References
Chapter 10. Image Guidance and Visualization in Pituitary Surgery
Introduction
Historical Evolution
Contemporary Image-Guidance Modalities
Future Directions
References
Chapter 11. Imaging and Epilepsy: The Key to Surgical Success
Introduction
Background
Advanced Neuroimaging
Discussion
Conclusions
References
Chapter 12. Image-Guided Open Cerebrovascular Surgery
Introduction
Aneurysms
Arteriovenous Malformations
Cavernous Malformations
Moyamoya
Discussion
Conclusion
References
Chapter 13. Functional Neurosurgery: Deep Brain Stimulation and Gene Therapy
Introduction
Deep Brain Stimulation
General Considerations in Frame-Based DBS
Preoperative Imaging and Target Selection
Interventional MRI-guided DBS
INTerventional MRI-guided Delivery of Gene Therapy Vectors
Discussion
References
Chapter 14. Image Guidance for Spine Surgery
Introduction
Types of Image Guidance in Spine Surgery
Applications of Image-guided Navigation in Spine Surgery
Specifics of Image Guidance
Conclusion
References
Chapter 15. Image-Guided Radiosurgery and Stereotactic Radiotherapy
Image-Guided Radiosurgery: Development and Applications of Linear Accelerator-Based SRS
Overview of Image-Guided Radiosurgical Technology
Procedural Steps
Broad Clinical Advantages of Image-Guided Radiosurgery
Conclusions
References
Chapter 16. MRI-Guided Stereotactic Laser Ablation
Introduction
History
Physical–Anatomical Principles of MRgLITT
Technical Considerations: Devices and Workflow
Choice of Stereotactic Platforms and Targeting Verification
Indications and Outcomes
Conclusion
References
Section III: New Directions
Chapter 17. Advances in Molecular Imaging for Surgery
Introduction
In Vivo Imaging Modalities
Future Directions
References
Chapter 18. Drug Delivery to the Brain via Focused Ultrasound
Introduction
Therapeutic Ultrasound
Focused Ultrasound in the Brain
Drug Delivery in the Brain: The Blood-Brain Barrier (BBB)
Image-Guided FUS
Future Developments and Perspectives
Conclusion
References
Chapter 19. Robotics for Image-Guided Neurosurgery
Introduction
Convergence of Technologies and Imaging in Neurosurgery
Image-guided Neurosurgery and Robotics
Toward an Ideal Neurosurgical Robot
Disclosure
References
Index
